An ordinary boy Yamada, is hospitalized with a fracture of both hands. He was also diagnosed with a certain “chronic disease” associated with pain in the testicles. To relieve the pain, he must ejaculate at least once every three hours. A nurse Tachibana is tasked to relieve Yamada from his pain whenever he desires.

You wouldn’t think that a hospital would be the setting for a series of erotic adventures, but when a new crop of nurses’ aides reports for duty, they’re confronted by an erotic lesson plan that pushes them to the brink of ecstasy… and sanity.

It is about a female doctor who is creating sex pills. There are two kinds, one pill for male sexual enhancement and one for female sexual enhancement. She plans on testing these pills on herself and four of nurses in her section. There is a catch, the pills can have strange side effects which can deform the body for more sexual pleasure.